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Your Metabolism Isn't Slow — It's Specific. ILSA Health Metabolic Efficiency DNA Test
Nutrition DNA · 43 Genetic Traits

Your metabolism isn't slow. It's specific.

Some bodies burn calories like a furnace. Some store them like a vault. Neither is broken. Both are genetic — and yours is finally readable.

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Genetic Traits
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BMR Heritability
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Lab Accuracy
— Mitochondrion — THE CELL'S POWERHOUSE BMR 1840 kcal UCP1 Active INSULIN Sensitive ATP Efficient
Why metabolism varies

Two bodies. Same calories. Different outcomes.

One person eats freely and stays lean. Another eats half as much and gains weight. The difference isn't discipline. It's mitochondrial wiring — the engine inside every cell that converts food to fuel.

01
Resting metabolic rate is 40 to 50% heritable. Two people of the same size, sex, and age can burn 200–400 different calories per day at rest — for purely genetic reasons.
02
Insulin sensitivity, glucose clearance, and fat-storage genetics determine whether your body uses a meal — or stores it. Same meal. Different ending.
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Mitochondrial efficiency, thermogenesis, and fat oxidation are all genetically calibrated. Knowing yours is the foundation of every metabolic protocol that actually works.
Your Metabolic Architecture

Does your engine burn — or does it conserve?

UCP1, AMPK, and ADRB3 variants split human metabolism into two architectures. Neither is broken. Both are real. Knowing yours stops the wrong protocol from costing you years.

Metabolic Signature · Thermogenic
Resting Calorie Burn
Post-Meal Thermogenesis
Fat-Burning Capacity
Glucose Clearance
Mitochondrial Efficiency

The thermogenic body.

Burns more at rest. Often runs warm. Hard to gain weight.

Thermogenic genotypes (UCP1 active variants, brown adipose tissue dominant, AMPK responsive) burn 200–400 more calories per day at rest than thrifty genotypes. The body wastes some calories as heat — which explains why you may run warm and why staying lean feels effortless. The trade-off: less efficient calorie storage means lower reserves during real fasting or food scarcity.

Strength
Easy lean maintenance
Trade-Off
Lower reserves
Best Strategy
Higher calorie · Frequent meals
Key Genes
UCP1 · ADRB3 · AMPK
The Metabolic Blueprint

43 genetic traits. Six categories. The complete metabolic map.

Every dot is one trait we decode. Energy output, glucose response, fat metabolism, nutrient utilization, appetite signaling, and cellular health — together they form the architecture of how your body actually runs.

All 43 traits

Your complete metabolic genome

Six categories. Forty-three traits. One DNA sample. Every dimension of how your body burns, stores, and uses energy — decoded once and yours forever.

What you'll learn

Six revelations hiding in your metabolic genome.

Hover (or tap) to flip each card. These are real examples of the kind of insight your report will deliver — built from peer-reviewed nutrigenomics and metabolic genetics research.

How loud is your internal furnace?

Hover to reveal →
Thermogenesis (UCP1)

The uncoupling protein gene controls how much energy your brown adipose tissue burns as heat instead of storing as fat. Active UCP1 variants run a "loud" furnace — easy to stay lean, harder to gain. Quieter variants store more efficiently. Either can be optimized once you know which you are.

Gene · UCP1

How well do you handle a sugar load?

Hover to reveal →
Glucose Response (TCF7L2)

The strongest single-gene predictor of type 2 diabetes risk and insulin sensitivity. Different variants shape how cleanly your body clears glucose from the bloodstream after a meal. Knowing yours informs everything from meal timing to carb load to whether intermittent fasting will actually serve you.

Gene · TCF7L2

Can your body actually access stored fat?

Hover to reveal →
Fat Breakdown (ADRB3)

The beta-3 adrenergic receptor gene governs lipolysis — the release of fat from storage for use as fuel. Slow variants make it harder to access fat stores during fasting or exercise; active variants release fat readily. This single gene shapes how your body responds to fasting, low-carb eating, and cardio.

Gene · ADRB3

Does your body store fat — or burn it?

Hover to reveal →
Fat Storage vs Burning (PPARG)

One of the master regulators of fat cell formation and fat metabolism. Different variants shape your body's bias toward storing energy as fat vs burning it for fuel. The Pro12Ala polymorphism specifically affects insulin sensitivity and your response to dietary fats and carbohydrates.

Gene · PPARG Pro12Ala

What time of day should you eat?

Hover to reveal →
Circadian Metabolism (CLOCK)

The CLOCK gene synchronizes your body's metabolic rhythm with the day-night cycle. Different variants shape when your insulin sensitivity peaks, when fat oxidation is highest, and whether late-night eating is metabolically harmless — or quietly disruptive. When you eat may matter as much as what.

Gene · CLOCK 3111T>C

How metabolically flexible are you?

Hover to reveal →
Metabolic Flexibility (ADIPOQ)

Adiponectin is the hormone that lets your body switch fuels efficiently — between glucose and fat — based on what's available. Higher-expression variants mean a more flexible metabolism that adapts quickly to fasting, exercise, and changing meals. Lower-expression variants are more rigid and benefit from steadier patterns.

Gene · ADIPOQ
The Cost of Metabolic Blindness

The science behind your engine.

Half of your metabolism was set the day you were born. The other half is what you do with it. Knowing the first half is what makes the second half matter.

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heritability of resting metabolic rate, established across hundreds of twin studies
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calorie-per-day difference between thermogenic and thrifty genotypes — that's 24 pounds per year of theoretical surplus or deficit
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of dieters regain the weight within 5 years — most because the protocol fought their metabolic wiring instead of working with it
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how many times you need to take this test. Your DNA does not change. Your report is forever.
Your Metabolic Type · 60 Seconds

A directional read on how your engine runs.

Five questions across five metabolic dimensions. We'll give you a composite metabolism score and a directional archetype. The exact genetic shape — the one your DNA reveals — is what the full test unlocks.

— Weight Tendency —
Historically, your body's relationship with weight has been:
Composite Metabolism Score
out of 100
Thermo-
genesis
Glucose
Tolerance
Fasting
Tolerance
Energy
Stability
Metabolic
Flex

— The Question Your DNA Answers —
What is the exact genetic shape behind this snapshot? Which protocols will compound with your metabolism instead of fighting it? That's what the report reveals — across all 43 traits, not five.
Decode My Metabolism — $249
How It Works

Four steps. No lab visit. No appointment.

A cheek swab from your kitchen. A prepaid mailer. A secure portal. That's the whole experience.

01

Order Online

Secure checkout. We ship your DNA collection kit to your door in 5–7 business days.

02

Swab at Home

A simple cheek swab. Two minutes. No needle. No appointment. No discomfort.

03

Mail It Back

Use the prepaid mailer. Drop it in any USPS box. We handle the rest from there.

04

Read Your Report

3–4 weeks later, your full metabolic genome report arrives by email and secure portal.

What You Receive

Not generic advice. Your metabolic manual.

Every recommendation is built from your genetic data — written so you can act on it tomorrow morning at breakfast, and share it with your physician or coach this week.

43 Trait Metabolic Genome Report

Detailed analysis of every genetic trait — energy output, glucose, fat metabolism, nutrient utilization, appetite, cellular health. References to the peer-reviewed research behind each insight.

Thermogenic vs Thrifty Profile

A clear read on which metabolic architecture your genome favors — and the calorie targets, meal timing, and macronutrient ratios that match your wiring instead of fighting it.

Fasting, Insulin & Meal Timing Guidance

Whether intermittent fasting will actually serve you. Whether late eating is harmless for your genome. How long your insulin sensitivity peaks last. The protocols backed by your DNA — not the latest trend.

Interactive Online Dashboard

HIPAA-compliant, secure portal. Access from any device. Share with your physician, dietitian, or coach in one click.

— Metabolic Genome Report —
Engine Profile
Metabolic Type
Thermogenic
Insulin Sensitivity
High
Fat-Burning Capacity (ADRB3)
Good
Thermogenesis (UCP1)
Active
Fasting Tolerance
Mid-High
Glucose Clearance (TCF7L2)
Good
Metabolic Flexibility
High
Who It's For

If you've ever felt your metabolism was the problem, this is the test.

The Metabolic Efficiency DNA test is recommended for weight loss and nutrition planning. It's especially valuable for these four people.

The person whose metabolism feels slow

You eat what your friends eat and gain twice as much. You diet and barely move the scale. Knowing whether your engine is genuinely thrifty — and what to do about it — turns a moral story into a mechanical one. The shame ends. The strategy begins.

The person on a GLP-1 protocol

GLP-1s suppress appetite and accelerate fat loss. Your metabolic genetics tell you how to eat during the protocol so you preserve muscle and energy — and how to maintain results after you taper. The answers are genuinely different for different genomes.

The biohacker or longevity person

Fasting, time-restricted eating, ketogenic protocols, cold exposure, mitochondrial optimization. You're already running advanced protocols. Your DNA tells you which of these will genuinely compound for your body and which are giving you placebo gains.

The person worried about blood sugar

Pre-diabetic flags. Family history. Glucose readings you'd rather not see. Your TCF7L2 variant and insulin-sensitivity genetics shape your risk path — and your most effective intervention. Knowing early is the highest-leverage move you can make.

Accreditation
CAP / CLIA
Lab Accuracy
99%+
Privacy
HIPAA secured
Research Base
Peer-reviewed
One Test · Forever Yours
— Metabolic Efficiency —

Your metabolic engine, decoded once.

$249.00
One Time · No Subscription · DNA Is Forever
43 genetic traits analyzed
Thermogenic vs thrifty profile
Glucose & insulin response map
Fasting & meal timing guidance
Personalized report (3–4 weeks)
Secure interactive dashboard
Order My DNA Test — $249
Secure SSL Checkout
All major cards accepted
HIPAA Compliant
Questions, Answered

What you're probably wondering.

Will this test diagnose diabetes or thyroid issues?

No — and that's an important distinction. This is a metabolic genetics report, not a clinical diagnostic. It reveals genetic predispositions (such as TCF7L2 variants linked to type 2 diabetes risk) but it does not diagnose any condition. If you have concerns about diabetes, thyroid, or any metabolic health issue, please consult a qualified clinician. The report can give you and your doctor a richer starting point — but it does not replace blood work or clinical evaluation.

Is this different from the Food Sensitivity test?

Both use the same underlying 43-trait Nutrition DNA panel, but the reports are framed for different questions. Food Sensitivity & Tolerance emphasizes what to eat — macronutrient response, food reactions, lactose, gluten, caffeine. Metabolic Efficiency emphasizes how your body runs — thermogenesis, insulin, glucose, fat metabolism, mitochondrial function, meal timing. Pick the one that matches the question you're trying to answer.

Can I take this if I'm on a GLP-1 medication?

Yes — and it's especially useful. Metabolic genetics tell you how to eat during a GLP-1 protocol to preserve muscle and energy, when to time meals around your circadian rhythm, and how to maintain the results after you taper. The combination is powerful.

How accurate is the lab work?

The testing is performed in a CAP/CLIA-accredited laboratory with greater than 99% accuracy. Every interpretation in your report is grounded in peer-reviewed nutrigenomics and metabolic genetics research. Your DNA and personal data are kept secure and HIPAA-protected at every step.

Will this tell me my actual BMR?

A real BMR measurement requires indirect calorimetry — a clinical test that measures the oxygen you consume at rest. What this test reveals is your genetic metabolic architecture: whether your wiring favors thermogenic or thrifty patterns, how your body handles glucose and fat, and the variants that shape your engine. Pair it with a real BMR test for full data, or use this on its own to guide protocol selection.

Do I need to take this more than once?

No. Your DNA does not change. One test gives you a report that is yours, forever. As metabolic science evolves, interpretations may be updated — but your underlying genetic data is a one-time investment.

Will the report help with intermittent fasting?

Yes. Your ADRB3 (fat breakdown), CLOCK (circadian metabolism), and AMPK pathway variants directly shape how well your body handles fasting. For some genomes, time-restricted eating compounds metabolic benefits. For others, it produces stress responses that disrupt energy and hormones. The report tells you which one you are.

How long until I get my results?

Approximately 3–4 weeks from the moment the lab receives your sample. You'll receive your full personalized report by email and through your secure online dashboard. Tracking is provided at every stage.

Where do you not ship?

Due to state regulations on direct-to-consumer genetic testing, we currently do not ship to New York, Pennsylvania, Rhode Island, or Maryland. Anywhere else in the United States is fine.

The Last Word

Stop fighting your metabolism. Decode it.

One cheek swab. Forty-three answers. The engine you've been trying to outrun all these years — finally readable, finally yours to work with instead of against.

Order My Metabolic Efficiency Test — $249
Secure Checkout · Results in 3–4 Weeks · CAP/CLIA Accredited Lab
This Nutrition DNA test is intended for informational and educational purposes related to diet, eating behaviors, metabolism, and general nutritional health. It is not a substitute for medical diagnosis, blood work, or professional medical advice, and is not designed to diagnose diabetes, thyroid disease, metabolic syndrome, or any other clinical condition. Results should be discussed with your physician or qualified healthcare provider before making significant changes to your diet, fasting protocols, or medications. ILSA Health does not ship to New York, Pennsylvania, Rhode Island, or Maryland.
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The health assessment offered through ILSA Health is designed for preliminary screening and educational purposes only. Completion of this questionnaire does not create a doctor–patient relationship.

All medical services, including clinical evaluations, treatment plans, and prescription decisions, are provided exclusively by independent U.S.-licensed healthcare providers. Providers exercise full medical judgment and determine eligibility based on individual clinical assessment and applicable state regulations.

If approved, prescriptions are dispensed by U.S.-based 503A compounding pharmacies that are registered with the FDA and operate in compliance with United States Pharmacopeia standards. Compounded medications are not FDA-approved and have not undergone FDA evaluation for safety, effectiveness, or manufacturing consistency.

Individual responses to treatment vary. No specific results are guaranteed.

ILSA Health does not manufacture, compound, or directly dispense medications. Product appearance, packaging, and labeling may vary from images shown on this website.

All trademarks and product names are the property of their respective owners.

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