It isn't laziness. It isn't bad form. It's ACTN3, ACE, COL5A1, and twenty-eight others. The wiring behind how your body trains and recovers is finally readable.
Two people, same gym, same coach, same diet. One adds muscle and recovers in 48 hours. The other stays sore for five days and pulls a hamstring every season. The variable isn't effort. It's ACTN3, COL5A1, and IL6. Wiring you didn't choose — and finally have language for.
Decades of exercise genetics show that humans cluster around two distinct training profiles: the Power athlete (ACTN3 RR, fast-twitch dominant, quick recovery) and the Endurance athlete (ACTN3 XX, slow-twitch dominant, aerobic efficiency). Most people are mixed. None of these is broken. Training the wrong protocol for your wiring is what wastes years.
Power-built bodies (ACTN3 RR carriers) express alpha-actinin-3 in fast-twitch muscle fibers — meaning peak force comes easily, muscle gains arrive faster, and short bursts feel natural. The trade-off: aerobic capacity rises slowly, and long steady-state cardio can feel like a fight. Sprinters, lifters, jumpers, throwers, and most professional power athletes skew here. The training that compounds for you is heavy lifting, short interval work, and protein-forward recovery — not high-volume cardio.
Every dot is one trait we decode. Muscle fiber composition, strength and power, endurance, recovery and inflammation, injury risk architecture, and weight loss metabolism — together they form the architecture of how your body responds to training.
Six categories. Thirty-one traits. One DNA sample. Every dimension of how your body builds muscle, burns fat, generates endurance, recovers from strain, and resists injury — decoded once and yours forever.
Hover (or tap) to flip each card. These are real examples of the kind of insight your profile will deliver — built from peer-reviewed exercise and sports genetics research.
The ACTN3 gene — often called "the speed gene" — codes for alpha-actinin-3, a protein in fast-twitch muscle fibers. The RR genotype is enriched in elite sprinters and power athletes. The XX genotype cannot produce the protein at all and is enriched in endurance athletes. Knowing yours tells you whether your body is wired for force or efficiency.
The angiotensin-converting enzyme gene has two main variants. The I (insertion) allele is overrepresented in elite endurance athletes — rowers, distance runners, climbers. The D (deletion) allele is overrepresented in sprinters and lifters. Your ACE profile tells you whether your cardiovascular system is built for the long burn or the short ignition.
The COL5A1 gene encodes type V collagen — a key structural protein in tendons, ligaments, and skin. Specific variants are repeatedly associated in research with elevated risk of Achilles tendinopathy, ACL injury, and other soft-tissue strains. Knowing yours doesn't mean you should stop training. It means your warm-up, your load progression, and your recovery should look different.
The interleukin-6 gene shapes how aggressively your body mounts and resolves the inflammatory response to training stress. Higher-inflammation variants mean stronger initial response but longer DOMS, slower turnaround, and more recovery cost per session. Lower-inflammation variants bounce back faster but may need higher training volume to drive adaptation. The right protocol depends on which you carry.
PPARGC1A encodes PGC-1α — often called the "master regulator" of mitochondrial biogenesis. It's the gene that decides how much new aerobic capacity your body builds in response to endurance training. Strong variants amplify your VO2 max trainability; weaker variants mean you have to work harder for the same aerobic gain. It's why two runners on the same program can end up in very different places.
The FTO gene is the most-replicated obesity-associated gene in humans. Specific variants are linked to higher baseline appetite, lower satiety after meals, and a more modest weight-loss response to the same training volume. Knowing yours doesn't excuse the work — it explains why you might need 20–30% more activity and tighter nutrition than someone with a different variant to see the same scale movement.
Roughly half of how your body trains and recovers is wiring you didn't pick. The other half is the program you build around it. The compounding only starts when both align.
Five questions across five dimensions. We'll give you a composite fitness profile and a directional archetype. The exact genetic shape — the one your DNA reveals — is what the full profile unlocks.
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A cheek swab from your kitchen. A prepaid mailer. A secure portal. That's the whole experience.
Secure checkout. We ship your DNA collection kit to your door in 5–7 business days.
A simple cheek swab. Two minutes. No needle. No appointment. No discomfort.
Use the prepaid mailer. Drop it in any USPS box. We handle the rest from there.
3–4 weeks later, your full recovery & injury risk fitness profile arrives via the secure portal.
Not generic fitness advice. Not influencer programs. A profile built from your genetic data — designed to inform how you train, how you recover, how you eat, and how you protect against injury.
Detailed analysis of every genetic trait — muscle fiber, strength, endurance, recovery, injury risk, and weight loss metabolism. Written in clear English with references to the peer-reviewed exercise and sports genetics research behind each insight.
A clear read on whether your body is wired primarily for explosive power or aerobic endurance — and how to build your weekly programming, intensity, and progression around the disposition you actually have.
Your COL5A1, COL1A1, IL6, and MMP3 genetics tell you where your soft tissue is most vulnerable and how aggressively your body resolves inflammation. The profile translates that into practical guidance: which warm-ups matter most for you, where to add load slowly, and what your real recovery window looks like.
HIPAA-compliant, secure portal. Access from any device. Share with your trainer, physical therapist, or doctor in one click.
The Recovery & Injury Risk profile is recommended for weight loss and fitness training. It's especially valuable for these four people.
Pulled hamstring last spring. Achilles flare-up. Shoulder that never quite came back. You're not careless — you might just be carrying COL5A1 or COL1A1 variants that load your soft tissue differently. The profile names exactly where your connective wiring is most exposed so you can train around it instead of into it.
You're in the gym five days a week. You're tracking food. The scale stays where it is. The profile decodes FTO, ADRB2, and fat-oxidation genes so you know whether your body is wired to lose with steady cardio, heavy strength work, or a metabolic mix — and stops you from running someone else's program against your own physiology.
Same program, same diet, same effort — and the bar won't move anymore. Plateaus are often a signal that your wiring needs a different stimulus. The profile tells you whether your ACTN3 / MSTN / IGF1 profile responds best to higher intensity, higher volume, or longer recovery between heavy days — and which lever to pull next.
You did a long session Saturday. You're still recovering Tuesday. Your IL6 and TNF variants might mean your inflammation response runs hotter and slower than average — which doesn't mean training less, it means training smarter. The profile gives you a real recovery window built around your biology, not the average athlete's.
No — and that's an important distinction. This is not a diagnostic test for any medical condition. It's a fitness-focused profile that decodes 31 genetic traits related to muscle composition, training response, injury risk, and recovery in healthy adults. If you have current injuries or medical concerns, please work with a qualified physician or physical therapist alongside the profile.
The Recovery & Injury Risk profile is the only ILSA test focused on physical performance and fitness genetics — ACTN3 muscle fiber, ACE endurance architecture, COL5A1 soft tissue, IL6 inflammation, FTO weight response, and the rest of the exercise-physiology panel. Other ILSA profiles (Motivation & Focus, Novelty-Seeking & Risk Tolerance, Behavior & Habit Formation) decode behavioral and personality genetics. Pick this one if your question is about training, injury, recovery, or weight loss — not personality.
No — it tells you where your body's natural advantage sits. ACTN3 RR is enriched in elite power athletes; ACTN3 XX is enriched in elite endurance athletes. But these are statistical tendencies, not destinies. Plenty of XX sprinters and RR marathoners exist. The point isn't to label you. It's to tell you which training stimulus your physiology responds to most efficiently — so you stop running someone else's program against your own wiring.
It will tell you the type of training your body responds to most efficiently (power vs endurance), how aggressively you can progress load, how long your real recovery window is, and where your soft tissue is most vulnerable. It will not replace a qualified strength coach or physical therapist — but it gives them (and you) a far more precise starting point than a generic intake form ever could.
Yes — and we encourage it. The profile gives a strength coach, personal trainer, physical therapist, or sports physician a precise genetics-informed starting point that conventional intake forms can't offer. It can accelerate the work, sharpen programming, and reduce trial-and-error. You stay in control of when and what to share.
It's designed to. The FTO, ADRB2, and fat-oxidation genes in your profile tell you why your body might respond strongly to one weight-loss strategy (heavy strength training, steady cardio, high-protein nutrition) and weakly to another. It is not a diet plan, and it does not replace the work — but it stops you from running protocols built for someone else's physiology and getting frustrated when the scale doesn't move.
Then the profile may be even more useful. You don't need to be elite to benefit from training that matches your wiring instead of fighting it. Whether you're starting fitness for the first time, returning after an injury, or trying to lose weight without keeping getting hurt — knowing your ACTN3, COL5A1, IL6, and FTO variants lets you build a program around the body you actually have, not the body in the workout videos.
The testing is performed in a CLIA-certified laboratory using established SNP (Single Nucleotide Polymorphism) analysis — the standard for ACTN3, ACE, COL5A1, IL6, FTO, and the rest of the panel. Every interpretation is grounded in peer-reviewed exercise and sports genetics research. Your DNA and personal data are kept secure and HIPAA-protected at every step.
No. Your DNA does not change. One test gives you a profile that is yours, forever. As exercise genetics research evolves, interpretations may be updated — but your underlying genetic data is a one-time investment.
Yes. The lab is CLIA-certified and your data is stored in a HIPAA-compliant system. We do not sell or share your genetic data. You are always the owner.
Due to state regulations on direct-to-consumer genetic testing, we currently do not ship to New York, Pennsylvania, Rhode Island, or Maryland. Anywhere else in the United States is fine.
One cheek swab. Thirty-one answers. The wiring behind how you train, how you recover, how you break, and how you build — finally readable. The next chapter of your fitness life starts with knowing the engine that's been running it.
Order My Fitness Profile — $249
The health assessment offered through ILSA Health is designed for preliminary screening and educational purposes only. Completion of this questionnaire does not create a doctor–patient relationship.
All medical services, including clinical evaluations, treatment plans, and prescription decisions, are provided exclusively by independent U.S.-licensed healthcare providers. Providers exercise full medical judgment and determine eligibility based on individual clinical assessment and applicable state regulations.
If approved, prescriptions are dispensed by U.S.-based 503A compounding pharmacies that are registered with the FDA and operate in compliance with United States Pharmacopeia standards. Compounded medications are not FDA-approved and have not undergone FDA evaluation for safety, effectiveness, or manufacturing consistency.
Individual responses to treatment vary. No specific results are guaranteed.
ILSA Health does not manufacture, compound, or directly dispense medications. Product appearance, packaging, and labeling may vary from images shown on this website.
All trademarks and product names are the property of their respective owners.
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